hCD2-iCre and Vav-iCre mediated gene recombination patterns in murine hematopoietic cells.
Cre-recombinase mediated conditional deletion of Lox-P site flanked ("floxed") genes is widely used for functional gene annotation in mice.Many different Cre-transgenic mouse lines have been developed for cell-type specific gene disruption.But often, the precise tissue-patterns of Cre activity remain incompletely characterized.Two widely used trans